Redmond

In January 2008, LANXESS Corp. acquired a small molecule development and production facility in Redmond, Washington which is operated by its business division Saltigo. Saltigo offers GMP Custom Manufacturing Unit for APIs to Support Preclinical Development, Clinical Phase I and II.

Location

• Redmond, WA (15 miles from Seattle)
• 1 Building with 20,000 sq ft
• Operated for GMP manufacturing of Small Molecule APIs since 1993
• Planned to be fully operational by Q1/2008

Analytical Development

• Multiple HPLCs
• HPLC/MS
• GC
• Ability to carry out most wet chemical analytical techniques
• Access to other analytical techniques

Chemical Development: Batches up to 20 L (max. 1 - 2 kg / batch)

• 10 bench-height hoods + 1 walk-in kilo hood
• Equipped with 3 HPLC and 1 HPLC/MS
• Ability to process up to 20 L in glassware
• HEL hazards evaluation reactor

GMP Kilolabs: Batches up to 100 L (max. 5 - 10 kg / batch)

• 2 GMP Kilolabs with 2 walk-in hoods and 1 bench-height hood each
• 50/100 L Glass reactors + 50 L separation vessel
• 12 L Pressure reactor
• 20 L rotary evaporator
• 12-inch centrifuge
• 4´chromatography column

GMP Pilot Plant: Batches up to 800 L (max. 20 - 80 kg / batch)

• 1 x 200 l glass-lined reactor
• 1 x 400 L glass-lined reactor
• 1 x 400 L glass-lined reactor for hydrogenation (up to 65 psi)
• 1 x 400 L Hastelloy C22 reactor equipped with TCU (-70°C to +170°C) (installed 2008)
• 1 x 800 L glass-lined reactor
• 2 x 400 L glass-lined receiver
• Aurora Hastelloy C22 26-inch filter
• 30-inch centrifuge
• 2 x Sparkler Pressure filter (80 psi)
• 2 x 132 sq ft. vacuum tray dryer (individually isolated)
• Fitz Mill for particle size reduction

Process Analytical Labs: IPC, GMP Analytics for Manufacturing

• HPLC
• GC/MS - HS-GC
• FTIR
• KF
• ROI muffle furnace
• Vacuum drying oven for LOD